Hotnews

endpoints

endpoints 44h ago 18°

Takeda is ‘not in favor’ of Trump’s MFN deals, CEO-designate says

Takeda’s incoming CEO took a firm stance against President Donald Trump’s “most favored nation” deals with drugmakers on Thursday, while Sanofi and Roche shared new details about their negotiations with the White House.
endpoints 44h ago 16°

Takeda is ‘not in favor’ of MFN, CEO-designate says

Takeda’s incoming CEO took a firm stance against President Donald Trump’s “most favored nation” deals with drugmakers on Thursday, while Sanofi and Roche shared new details about their negotiations with the White House.
endpoints 48h ago 12°

AstraZeneca makes $15B bet on China to expand manufacturing and R&D

AstraZeneca, already one of the leading pharmaceutical companies in China, is extending its reach in the country that's become a go-to place for drug R&D and industry dealmaking in the past year.
endpoints 46h ago 11°

Sanofi vows to stay committed to vaccines as portfolio takes a hit

Sanofi CEO Paul Hudson emphasized the company’s commitment to vaccine development in the face of an increasingly challenging sales environment and its decision to abandon an mRNA-based flu vaccine program.
endpoints 20h ago 10°

Bitterroot reverts to preclinical biotech in CD47 as CEO leaves

Bitterroot Bio, a biotech from leading minds in the CD47 field, appears to have returned to the discovery stage after attempting to expand the potential of the "don't eat me" signal from the cancer field ...
endpoints 19h ago 10°

FDA says it explained issues early on for Corcept's rejected Cushing's syndrome drug

An FDA rejection letter for Corcept Therapeutics’ potential hormonal disorder drug says the agency told the company it had serious concerns before the application was submitted.
endpoints 46h ago 10°

The disrupted fate of pharmacy startups

Last week, the House Judiciary Committee came out with a report about CVS Health’s alleged antitrust behavior toward disruptive pharmacy models that provide digital services to other pharmacies. It details ...
endpoints 21h ago

Ultragenyx resubmits gene therapy for rare neuro disease to FDA

Ultragenyx has resubmitted its approval request for a rare disease gene therapy after the FDA rejected it last summer.
endpoints 22h ago

Lilly unveils $3.5B factory that will make retatrutide and other obesity drugs

Eli Lilly has budgeted $3.5 billion for a new weight loss injectable and device factory in Lehigh Valley, PA, which will manufacture its next-gen obesity drug retatrutide.
endpoints 3h ago

Big Pharma earnings kick off; Third-round IRA drugs selected; Hengrui’s trailblazing moment; and more

Welcome back to Endpoints Weekly! Fourth-quarter earnings season is in full swing, and our team covered reports this week from Teva, Roche, Sanofi, Takeda and Regeneron. CMS also unveiled the next 15 drugs subject to ...
endpoints 47h ago

Summit gets November PDUFA date for its PD-1xVEGF bispecific

The leader in the next frontier of immuno-oncology officially has a date with the FDA.
endpoints 26h ago

Janux hires CMO after T cell engager deal with Bristol Myers; A batch of appointments at Lexeo

→ William Go has replaced Zachariah McIver as CMO of Janux Therapeutics, a San Diego-based biotech that is partnering with Bristol Myers Squibb on a T cell engager ...
endpoints 22h ago

Amgen ends partnership with Kyowa Kirin on immunology drug, despite Phase 3 wins

Amgen abruptly pulled out of a collaboration for a leading drug in its immunology pipeline on Friday, sending the asset back to its partner ahead of an FDA submission later this year.
endpoints 22h ago

Quince's steroid therapy for rare disease fails, shares tank

Quince Therapeutics' once-monthly steroid-based treatment failed a Phase 3 trial for a rare genetic condition called ataxia-telangiectasia, prompting the Bay Area company to say it would stop development of the experimental ...
endpoints 43h ago

Takeda 'anticipated' Medicare negotiations for top seller Entyvio

Incoming Takeda CEO Julie Kim says the drugmaker "anticipated" this week's selection of Entyvio for Medicare negotiations. But for now, the company isn't ready to comment on how the process could affect peak revenue forecasts ...
endpoints 27h ago

AstraZeneca pays $1.2B for CSPC's long-acting obesity drugs

AstraZeneca is already delivering on its $15 billion commitment to China with a $1.2 billion upfront pact with CSPC Pharmaceutical, spanning eight drug programs and multiple platform technologies.
1 2